STN inhibition in a DD mouse (1) from mpep Watch Video
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Description: Brief description:nWe inhibited the subthalamic nucleus (STN) of a dopamine-deficient (DD) mouse.Although DD mice are profoundly hypoactive and hypophagic in the absence of brain dopamine, inhibition of the STN resulted in almost immediate onset of locomotion, and feeding.This video begins approximately 1.5 minutes after the drug has reached the STN.Behavioral effects of the drug during the first minute included whisker movements and sniffing.At the beginning of this sequence, the mouse