Movie S9 | Primordial germ cell migration during mouse embryonic development from nls Watch Video
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Description: Visualization of primordial germ cell (PGC) migration in a dual-expressing Sox2-eGFP and mKate2-nls mouse embryo (posterior view). PGCs can be first seen in the proximal posterior region around time 04:00:00. A few PGCs appear to be pulled into the extraembryonic region during amnion inflation, while the remainder go on to divide and send out small protrusions but largely remain in the same area until they are drawn inward during the formation of the hindgut portal around 30:00:00. Time is repre