STN inhibition in a DD mouse (2) from mpep Watch Video
Preview(s): Play Video: (Note: The default playback of the video is HD VERSION. If your browser is buffering the video slowly, please play the REGULAR MP4 VERSION or Open The Video below for better experience. Thank you!)
Your browser does not support playing the video.Please download the video!
Description: Brief description:nWe inhibited the subthalamic nucleus (STN) of a dopamine-deficient (DD) mouse.Although DD mice are profoundly hypoactive and hypophagic in the absence of brain dopamine, inhibition of the STN resulted in almost immediate onset of locomotion, and feeding.This video begins approximately 3 minutes after the drug has reached the STN.The mouse has already begun to explore the cage, and to groom.At the beginning of this sequence, the experimenter placed several pellets of fo